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Term Information

Accession
GO:0001586
Name
Gi/o-coupled serotonin receptor activity
Ontology
molecular_function
Synonyms
5-HT1 receptor activity, serotonin receptor activity, coupled via Gi/o
Alternate IDs
None
Definition
Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels. Source: PMID:18571247, GOC:mah
Comment
None
History
See term history for GO:0001586 at QuickGO
Subset
None
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Parents of Gi/o-coupled serotonin receptor activity (GO:0001586)
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Gi/o-coupled serotonin receptor activity [is_a relation] is_a  G protein-coupled serotonin receptor activity (GO:0004993)

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