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Term Information

Accession
GO:0044824
Name
retroviral 3' processing activity
Ontology
molecular_function
Synonyms
3' processing reaction, 3'-processing activity
Alternate IDs
None
Definition
The catalysis of the removal of two di- or tri-nucleotides from each 3' end of double-stranded viral DNA, exposing recessed 3' hydroxyls. Source: Reactome:R-HSA-164522, PMID:22580823
Comment
This reaction may serve to remove heterogeneous extra bases from the viral DNA end, and to stabilize the integrase-DNA complex. The chemistry of cleavage is a simple hydrolysis by single-step transesterification.
History
See term history for GO:0044824 at QuickGO
Subset
None
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Graph of GO:0044824

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Parents of retroviral 3' processing activity (GO:0044824)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
retroviral 3' processing activity [BFO:0000050 relation] BFO:0000050  retroviral integrase activity (GO:0044823)
retroviral 3' processing activity [is_a relation] is_a  DNA endonuclease activity (GO:0004520)

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