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amylin receptor 3 signaling pathway
Term Information
Accession
GO:0150061
Name
amylin receptor 3 signaling pathway
Ontology
biological_process
Synonyms
AMY3 signaling pathway
Alternate IDs
None
Definition
The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 3 (AMY3), a G protein-coupled receptor complex, on the surface of the target cell. The AMY3 signaling pathway can also be initiated by the amyloid-beta complex. AMY3 signaling results in increased import of calcium ions into the cytosol across plasma membrane, increased phosphorylation of ERK1/2, Act, and a PKA regulatory subunit II, as well as increased expression of cFos.
Source:
GOC:bc,
PMID:22500019,
GOC:aruk
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