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Term Information

Accession
GO:0036462
Name
TRAIL-activated apoptotic signaling pathway
Ontology
biological_process
Synonyms
TRAIL-activated extrinsic apoptotic signaling pathway, TRAIL-induced apoptotic signaling pathway, tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway
Alternate IDs
None
Definition
An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface. Source: GOC:PARL, GOC:bf, PMID:21785459
Comment
None
History
See term history for GO:0036462 at QuickGO
Subset
None
Feedback
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Graph of GO:0036462

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Parents of TRAIL-activated apoptotic signaling pathway (GO:0036462)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
TRAIL-activated apoptotic signaling pathway [is_a relation] is_a  extrinsic apoptotic signaling pathway via death domain receptors (GO:0008625)
Children of TRAIL-activated apoptotic signaling pathway (GO:0036462)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
TRAIL receptor activity (GO:0036463) [BFO:0000050 relation] BFO:0000050  TRAIL-activated apoptotic signaling pathway
TRAIL death-inducing signaling complex assembly (GO:1903074) [BFO:0000050 relation] BFO:0000050  TRAIL-activated apoptotic signaling pathway
negative regulation of TRAIL-activated apoptotic signaling pathway (GO:1903122) [RO:0002212 relation] RO:0002212  TRAIL-activated apoptotic signaling pathway
positive regulation of TRAIL-activated apoptotic signaling pathway (GO:1903984) [RO:0002213 relation] RO:0002213  TRAIL-activated apoptotic signaling pathway
regulation of TRAIL-activated apoptotic signaling pathway (GO:1903121) [RO:0002211 relation] RO:0002211  TRAIL-activated apoptotic signaling pathway
None.